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March 3, 2026Lupus Science & Medicine4 citationsOpen Access

Real-world experience with belimumab-based triple therapy in proliferative lupus nephritis: data from the BEL-SPAIN Registry

PVPaola Vidal-MontalBellvitge University HospitalAFAina FabregatBellvitge University HospitalIAIrene Altabás-GonzálezUniversidad de Las Palmas de Gran Canaria

Key Points

  • High renal response rates were observed with belimumab-based triple therapy, indicating its effectiveness.
  • Extrarenal response rates also showed substantial improvement, emphasizing comprehensive treatment benefits.
  • Data analysis from the BEL-SPAIN Registry highlights real-world efficacy and safety in clinical practice.
  • Effects demonstrate potential for increased GC-sparing outcomes and treat-to-target strategies in therapy.

Abstract

BEL-based triple therapy is effective and safe in proliferative LN, achieving high renal and extrarenal response rates, substantial GC-sparing and treat-to-target outcomes in real-world practice.

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Cite This Study

Vidal-Montal et al. (2026) studied this question.

synapsesocial.com/papers/69a75b7fc6e9836116a22ed1https://doi.org/10.1136/lupus-2025-001825
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