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March 3, 2026Cell Communication and Signaling1 citationsOpen Access

BPC157 drives angiogenesis through FBXO22-dependent stabilization of BACH1

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JZJieyu ZhangMLMengmeng LiuHOHuihui Ou

Key Points

  • Angiogenesis results from BPC157's effect on FBXO22 and BACH1 stabilization, promoting new blood vessel formation.
  • The study shows a significant increase in angiogenesis, with results indicating a 30% enhancement in endothelial cell function.
  • Experimental models demonstrated the molecular pathways through which FBXO22 influences BACH1 stabilization.
  • The findings highlight the potential for BPC157 as a therapeutic agent targeting angiogenic processes, although further clinical trials are needed.
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Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69a75bacc6e9836116a23751https://doi.org/10.1186/s12964-026-02694-6
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