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March 3, 2026JAMA Surgery37 citations

Diagnosis and Treatment of Acute Appendicitis

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MPMauro PoddaUniversity of CagliariMCMarco CeresoliJKJames KynastonUniversity Hospitals Birmingham NHS Foundation Trust

Key Points

  • Effective diagnosis and treatment protocols for acute appendicitis are essential to improve patient outcomes, and thus need standardization.
  • The 2025 WSES Jerusalem Guidelines emphasize the importance of adapting practices to local health care systems and resources.
  • Implementing these guidelines may reduce variability in care for acute appendicitis, benefiting diverse patient populations.
  • Patient-centered care is a crucial focus, aiming for safer and more effective treatment options for acute appendicitis.

Abstract

The 2025 WSES Jerusalem Guidelines provide updated, evidence-based recommendations for the diagnosis and treatment of acute appendicitis with the aim to standardize practice, reduce unwarranted variability, and support safe, effective, and patient-centered care across diverse populations and health care systems. Their implementation should be adapted to local resources.

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Cite This Study

Podda et al. (2026) studied this question.

synapsesocial.com/papers/69a75c78c6e9836116a2561fhttps://doi.org/10.1001/jamasurg.2025.6218
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