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March 3, 2026Frontiers in Immunology5 citationsOpen Access

Extraction, purification, structural elucidation, and immunomodulatory activity of Bletilla striata polysaccharides via the NF-κB signaling pathway

GPGuofeng PangGuiyang College of Traditional Chinese MedicineKZKai ZhouGuiyang College of Traditional Chinese MedicineDGDi GaoGuiyang College of Traditional Chinese Medicine

Key Points

  • Bletilla striata polysaccharides demonstrate a balancing effect on pro-inflammatory responses, suggesting their therapeutic potential.
  • Key evidence reveals the modulation of inflammation through the NF-κB signaling pathway by these polysaccharides.
  • This analysis utilizes structural elucidation techniques to determine the properties of the polysaccharides effectively.
  • The findings indicate significant implications for these polysaccharides in developing functional foods aimed at immune regulation.

Abstract

These results demonstrate that BSP-2 balances pro-inflammatory responses via the NF-κB pathway, supporting its promising application as a bioactive immunoregulatory component in functional food and dietary supplement development.

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Cite This Study

Pang et al. (2026) studied this question.

synapsesocial.com/papers/69a75c9fc6e9836116a25a2chttps://doi.org/10.3389/fimmu.2026.1749545
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