This study indicates that among the interventions for treating hyperthyroidism, I-131+LC has a higher efficacy rate compared to other treatments, I-131+PTU is superior in reducing FT3, increasing TSH and reducing adverse reactions compared to other treatments. Due to the limitations in the quantity and quality of the included studies, the aforementioned conclusions await further validation from more large-sample, high-quality, and multicenter studies. PROSPERO study number CRD42024566298.
Zhang et al. (2026) studied this question.