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March 3, 2026Respirology Case Reports0 citationsOpen Access

AFI ‐Guided Detection and Biopsy of Pulmonary MALT Lymphoma With Bilateral Endobronchial Involvement

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LSLynn Y. W. ShongKLK. M. LamRHRyan C. W. Ho

Key Points

  • Complete metabolic response observed after rituximab treatment shows the effectiveness of this approach.
  • AFI bronchoscopy identified bilateral endobronchial lesions leading to a confirmed diagnosis of MALT lymphoma.
  • Patient presenting with blood-stained sputum underwent PET CT revealing a right upper lobe lesion without nodal disease.
  • The case highlights the importance of utilizing advanced imaging techniques for early diagnosis of pulmonary conditions.

Abstract

A 74-year-old man with prior stage IE gastric MALT lymphoma presented with blood-stained sputum. Autofluorescence imaging (AFI) bronchoscopy revealed bilateral endobronchial lesions; with biopsies confirmed MALT lymphoma. Positron emission tomography computed tomography showed right upper lobe lesion without nodal disease. He received rituximab, with complete metabolic response. AFI facilitated early airway-focused diagnosis.

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Cite This Study

Shong et al. (2026) studied this question.

synapsesocial.com/papers/69a75d14c6e9836116a26888https://doi.org/10.1002/rcr2.70486
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