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March 3, 2026Angiogenesis1 citationsOpen Access

Endothelial USP8 is essential for angiogenesis

APAlba Pau-NavalónInstituto de Salud Carlos IIITGTamara González-CostaCentro de Investigación en Red en Enfermedades CardiovascularesMLMaría Lancho LavillaTechnical University of Munich

Key Points

  • Endothelial USP8 is essential for angiogenesis, influencing vascular development and integrity.
  • Significant findings demonstrate that disruption of USP8 impairs blood vessel formation in experimental models.
  • Analysis of endothelial cell behavior reveals the involvement of USP8 in critical molecular pathways driving angiogenesis.
  • Understanding USP8's role may open new avenues for targeting vascular-related diseases, emphasizing potential therapeutic strategies.
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Cite This Study

Pau-Navalón et al. (2026) studied this question.

synapsesocial.com/papers/69a75d1ec6e9836116a269e7https://doi.org/10.1007/s10456-025-10027-3
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