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March 3, 2026Dermatologic Surgery1 citations

Does Hormone Replacement Therapy Influence Melasma Development? A Review of the Evidence and Management Guidelines

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SASabriya AbdeenESE. ShaoDLDavin Lim

Key Points

  • Melasma risk is increased in women receiving hormone replacement therapy, and more studies are needed.
  • A strong emphasis should be placed on photoprotection measures for women at risk of developing melasma.
  • Prospective studies aim to clarify the relationship between various hormone replacement therapy formulations and melasma.
  • Counseling at-risk women is crucial for preventing the onset of melasma and enhancing treatment outcomes.

Abstract

HRT-associated melasma is underrepresented in the literature. Clinicians should counsel at-risk women on melasma risk and ensure strict photoprotection. Prospective studies are needed to clarify melasma risk across different HRT formulations.

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Cite This Study

Abdeen et al. (2026) studied this question.

synapsesocial.com/papers/69a75d3bc6e9836116a26ed3https://doi.org/10.1097/dss.0000000000005032
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