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March 3, 2026Journal of Allergy and Clinical Immunology0 citations

Age-dependent differences in airway inflammation and function in severe uncontrolled asthma

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JBJôse Mára de BritoUniversidade de TaubatéNCNatália de Souza Xavier CostaHospital das Clínicas da Faculdade de Medicina da Universidade de São PauloDFDiogenes S. FerreiraHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Key Points

  • Airway inflammation is significantly different between age groups, impacting overall lung function.
  • In children, severe asthma shows higher levels of inflammation compared to adults, with implications for treatment strategies.
  • Observational analysis highlights the relationship between age and immune responses in severe uncontrolled asthma.
  • Findings suggest that age-specific approaches may enhance management and improve outcomes in asthma.
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Cite This Study

Brito et al. (2026) studied this question.

synapsesocial.com/papers/69a75e95c6e9836116a2954dhttps://doi.org/10.1016/j.jaci.2025.12.1015
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