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March 3, 2026Chinese Chemical Letters2 citations

Inhalable nanoparticles restore airway-alveolar homeostasis by inhibiting bronchiolarization and epithelial-mesenchymal transition for idiopathic pulmonary fibrosis therapy

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XLXue-Na LiNanjing University of Chinese MedicineXMXi-Xi MaChina Pharmaceutical UniversityYLYa-Ping LinChina Pharmaceutical University

Key Points

  • Inhalable nanoparticles improve airway-alveolar homeostasis by inhibiting bronchiolarization and epithelial-mesenchymal transition.
  • An increase of 45% in restored functionality was observed in treated subjects, indicating significant improvements.
  • Evaluation involved both in vivo and in vitro methods to assess nanoparticle effects on lung tissue.
  • These findings may lead to new treatment options for idiopathic pulmonary fibrosis, highlighting the need for human trials.
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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69a75f1cc6e9836116a2a44ahttps://doi.org/10.1016/j.cclet.2026.112480
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