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March 3, 2026Molecular Biomedicine15 citationsOpen Access

TGF-β in tumor development and progression: mechanisms and therapeutics

JLJialing LiuYWYiwei WangCTChao Tang

Key Points

  • Tumor progression is driven by TGF-β signaling pathways, influencing cellular behavior and microenvironment.
  • Key evidence shows that high TGF-β levels correlate with increased tumor growth in various cancers.
  • Analysis of biological mechanisms reveals TGF-β's complex role in immune evasion and metastasis.
  • Understanding TGF-β could lead to targeted therapies, enhancing cancer treatment options and patient outcomes.
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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69a75f4dc6e9836116a2a947https://doi.org/10.1186/s43556-026-00403-w
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