Optimized stimulation using C3/4 → Cz reduces the risk of false-negative monitoring during surgery.
False-negative monitoring risks are particularly associated with deep white matter stimulation.
This observational analysis highlights the importance of stimulation selectivity in enhancing TcMEP reliability.
Further assessment of techniques may enable safer surgical procedures with improved patient outcomes.
Abstract
This study supports using C3/4 → Cz to optimize TcMEP selectivity and reduce the risk of false-negative monitoring due to deep white matter stimulation.