BK Polyomavirus Escapes Immune Response and Prolongs Cell Survival through Interferon-Regulated Gait Complex and Sirtuin Signaling

Key Points

• BK polyomavirus escapes immune detection, enhancing cell survival against host defenses.
• Key metrics include enhanced cell longevity and interferon-mediated response modulation.
• Analysis reveals interactions between gait complex and sirtuin signaling in immune evasion.
• This may enable novel strategies for managing viral infections and clinical implications for patients.