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March 3, 2026Journal of Minimally Invasive Gynecology0 citationsOpen Access

Surgical complications of salpingo-oophorectomy in women undergoing risk-reducing surgery for hereditary breast and ovarian cancer - A retrospective cohort study

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ALAnna Katrine Holst LundKNKlara Vinsand NaverKPKresten Rubeck Petersen

Key Points

  • Overall complication rate was low at 6.09%, indicating safety in risk-reducing surgery.
  • Of the 15 complications, 60% were classified as minor (Clavien Dindo grade I), and 40% required antibiotic treatment (grade II).
  • Retrospective cohort study analyzed 246 women undergoing risk-reducing salpingo-oophorectomy and related surgeries.
  • Findings support counseling for women with hereditary breast and ovarian cancer, emphasizing low risks associated with RRSO.

Abstract

Risk reducing bilateral/unilateral salpingoophorectomy ± hysterectomy RESULTS: 246 women underwent surgery, and 15 (6.09%) experienced complications. 9 (60%) were Clavien Dindo grade I and 6 (40%) grade II. No grade III, IV, or V complications occurred. Grade I included minor pain or superficial infection not requiring antibiotic treatment, and grade II were all due to infections requiring treatment with antibiotics. No significant differences were found between women with and without complications with respect to age, BMI, previous abdominal surgery or smoking CONCLUSION: The incidence and severity of complications after risk reducing surgery were low. This evidence is valuable in counseling women with HBOC and offers reassurance about the safety of RRSO.

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Cite This Study

Lund et al. (2026) studied this question.

synapsesocial.com/papers/69a76073c6e9836116a2d334https://doi.org/10.1016/j.jmig.2026.01.052
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