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March 3, 2026Frontiers in Pharmacology0 citationsOpen Access

Beyond antipsychotic efficacy and toward an individualized therapeutic strategy: analysis of the systemic, metabolic, and inflammatory effects of olanzapine, haloperidol, and their combination in schizophrenic patients

NANayef Samah AlharbiAmerican Association of Colleges of PharmacyNHNoha Alaa HamdyAmerican Association of Colleges of PharmacyEAEsam M. AboubakrSouth Valley University

Key Points

  • Optimized clinical outcomes depend on understanding systemic effects.
  • Individualized therapy may reduce long-term risks associated with antipsychotics.
  • Evaluation of olanzapine and haloperidol shows differences in metabolic effects.
  • Insights into inflammation may inform better treatment for schizophrenia.

Abstract

This study provides valuable insights into the systemic, metabolic, and inflammatory effects of tested drugs, support the individualized therapeutic approaches in schizophrenic patients to optimize clinical outcomes and minimizing long-term systemic risks.

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Cite This Study

Alharbi et al. (2026) studied this question.

synapsesocial.com/papers/69a7609bc6e9836116a2d831https://doi.org/10.3389/fphar.2026.1727959
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