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Synapse
March 3, 20260 citationsOpen Access

Kauro, a graph-based chatbot for high-fidelity information transmission conversations

PAPeter M. AndersonCleveland ClinicRBRebecca BarrickYCYa CuiShenyang Institute of Engineering

Key Points

  • Kauro enhances informed consent processes with structured, reproducible conversations, minimizing errors.
  • The chatbot functions using version-controlled JSON structures, enabling deterministic and traceable interactions.
  • Observational analysis of chat interactions shows reduced variability and improved adherence to ethical standards.
  • Kauro's design supports scalability in various domains, emphasizing safety and trust in communication.

Abstract

Across biomedical research and care, many conversations transmit information with profound practical, ethical, and legal consequences. The process of informed consent, where individuals decide to join a study or accept clinical care, is perhaps the most consequential, yet it is also complex, labor-intensive, and variable across sites. Existing platforms for information transmission in the informed consent context largely reproduce static documents and lack reproducibility or auditability, while generative chatbots offer flexibility at the cost of stochasticity, hallucination, and regulatory risk. We present Kauro, an open-source, graph-based chatbot that encodes scripted conversations as version-controlled JavaScript Object Notation (JSON) structures, enabling deterministic traversal (ie, paths through the graph), complete audit logging, and IRB-verifiable oversight. Its modular separation of client, server, and script ensures portability across institutions. By operationalizing constraint rather than flexibility, Kauro reframes deployment of machine intelligence in biomedical communication with reproducibility and auditability, offering a scalable platform generalizable to any domain where conversations demand safety, precision, and trust.

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Cite This Study

Anderson et al. (2026) studied this question.

synapsesocial.com/papers/69a765d4badf0bb9e87daa1chttps://doi.org/10.64898/2026.01.30.25342358
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