PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 3, 2026Frontiers in Immunology0 citationsOpen Access

Effective treatment of acute graft-versus-host disease following liver transplantation using an integrated regimen centered on antithymocyte globulin: a single-center experience

QZQiming ZhengLZLi ZhangHWHonghai Wang

Key Points

  • ATG-based therapy improved outcomes in acute graft-versus-host disease after liver transplantation, indicating its potential effectiveness.
  • Patients receiving antithymocyte globulin had better responses than those on conventional treatments, highlighting the need for further studies.
  • Integrated diagnosis included examining clinical symptoms and chimerism detection to confirm acute graft-versus-host disease.
  • Future research may focus on large-scale evaluations to validate the promising results observed in this series.

Abstract

The diagnosis of aGVHD after LT requires integrating clinical manifestations, rash pathology, and chimerism detection. In this small series, ATG-based therapy was associated with favorable outcomes compared with a historical cohort receiving conventional therapy, suggesting that it may be a promising strategy warranting further evaluation in large-scale clinical studies.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Zheng et al. (2026) studied this question.

synapsesocial.com/papers/69a7668fbadf0bb9e87dd750https://doi.org/10.3389/fimmu.2026.1696936
Ask AI
Helpful
Bookmark
Share
View Full Paper