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Synapse
March 3, 20260 citations

Gestasyonel ve pregestasyonel diyabette Caval Aort İndeksinin ultrasonografik değerlendirmesi: perinatal sonuçları öngörebilir mi?

GKGülşan KarabayZŞZeynep ŞeyhanlıAFAhmet Arif Filiz

Key Points

  • Pregnant women with diabetes have higher caval aortic index values than controls, indicating altered hemodynamics and potential risks for perinatal complications.
  • In this study, differences in inferior vena cava and aortic diameters were statistically significant, with p-values indicating robust statistical relevance.

Structured PICO

Can the Caval Aortic Index and ultrasound measurements of IVC and aorta predict adverse perinatal outcomes in diabetic pregnant women?

P
Population
220 pregnant women, comprising 120 with diabetes mellitus (pre-gestational, diet-regulated gestational, and insulin-regulated gestational diabetes) and 100 healthy controls.
I
Intervention
Ultrasound measurement of inferior vena cava (IVC) and aortic (Ao) diameters, and calculation of the Caval Aortic Index.
C
Comparator
Healthy pregnant controls (n=100).
O
Outcome
Functional changes in IVC and aorta diameters and prediction of adverse perinatal outcomes.surrogate

IVC and aortic diameters are significantly higher in pregnant women with diabetes compared to healthy controls, suggesting potential utility of these measurements in assessing vascular changes.

Abstract

Aims: Diabetes mellitus (DM), including gestational (GDM) and pregestational diabetes (pre-GDM), adversely affects maternal and fetal outcomes due to hyperglycemia and vascular changes. The Caval Aortic Index, a non-invasive measure of blood volume, could provide insights into these complications. In our study, we aimed to determine the functional changes in inferior vena cava (IVC) and aorta (Ao) diameters as well as the importance of caval aortic index in predicting perinatal outcomes in diabetic pregnant women.Methods: This prospective case-control study included 120 DM patients and 100 controls. DM patients were divided into pre-GDM, diet-regulated GDM, and insulin-regulated GDM groups. Ultrasound measurements of inferior vena cava and aortic diameters were performed, alongside Doppler evaluations. Statistical analyses were conducted to assess the association of these parameters with adverse perinatal outcomes.Results: Although the IVC and aortic diameters of the pregnant women with DM were higher compared to the control group and a statistically significant difference (p

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Cite This Study

Karabay et al. (2025) studied this question.

synapsesocial.com/papers/69a766a4badf0bb9e87ddcbf
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