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March 3, 2026World Journal of Gastroenterology1 citationsOpen Access

Anatomical laterality of primary intestinal diffuse large B-cell lymphoma independently stratifies survival: New prognostic nomogram incorporating tumor location

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RZRui-Xin ZengCWCaiqin WangHYHang Yang

Key Points

  • Survival is independently linked to intestinal laterality in primary intestinal diffuse large B-cell lymphoma, emphasizing its importance.
  • The prognostic nomogram achieved higher discrimination than the International Prognostic Index, enhancing individual survival predictions.
  • Risk stratification incorporates tumor location, allowing more tailored management approaches for patients.
  • Findings support using anatomical factors in prognosis, though specific external validations are needed.

Abstract

Intestinal laterality is an independent, clinically actionable determinant of survival in PI-DLBCL. The proposed nomogram provides individualized survival prediction and risk stratification and showed higher discrimination than the IPI, supporting the incorporation of tumor anatomical location into prognostic assessment and risk-adapted management.

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Cite This Study

Zeng et al. (2026) studied this question.

synapsesocial.com/papers/69a766ffbadf0bb9e87df407https://doi.org/10.3748/wjg.v32.i7.115406
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