Is random biopsy necessary for normal esophageal mucosa during chromoendoscopy? Evidence from a population-based cohort study

Key Points

• The aim is to evaluate the necessity of random biopsies in normally stained esophageal mucosa during chromoendoscopy in ESCC screening.
• Conducted a population-based cohort study
• Utilized Lugol's chromoendoscopy for evaluations
• Assessed esophageal mucosa findings
• Random biopsies of normal mucosa were found to be unnecessary
• Findings suggest effectiveness in esophageal squamous cell carcinoma screening