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March 4, 2026Nano Research1 citationsOpen Access

Skin-attachable OLED electroceutical for chronic dermatitis treatment

YSYe Ji ShinKKKyeong Ah KimHKHyun Jung Kim

Key Points

  • The aim is to evaluate the effectiveness of a wearable OLED patch for treating chronic dermatitis conditions like psoriasis and atopic dermatitis.
  • Developed a flexible OLED patch with a built-in battery for self-operation and reusability.
  • Conducted daily light irradiation at 632 nm in mouse models of chronic dermatitis.
  • Monitored changes in epidermal thickness and transepidermal water loss (TEWL).
  • Assessed inflammatory cytokine levels (IL-4, IL-17, IL-22) to determine treatment effects.
  • Significant recovery of epidermal thickness was observed in treated mouse models.
  • Transepidermal water loss (TEWL) returned to near-normal levels after treatment.
  • Expression of inflammatory cytokines (IL-4, IL-17, IL-22) was suppressed, indicating reduced inflammation.

Abstract

Wearable electroceuticals are emerging as a key platform for health management due to their safety and non-invasiveness, with therapeutic efficacy enhanced by close skin contact. In this study, we present a wearable organic light-emitting diode (OLED) patch that integrates flexible hardware and a flexible battery for self-operation and reusability. The OLED exhibits excellent mechanical flexibility, adhering intimately to the skin while maintaining a safe temperature range of 20 °C at 5 mW/cm2, stable operation for over 1,000 h, and high moisture resistance. Daily irradiation with 632 nm OLED light (9 J/cm2) in mouse models of psoriasis and atopic dermatitis (AD) led to significant recovery of epidermal thickness and transepidermal water loss (TEWL) to near-normal levels. The expression of inflammatory cytokines (IL-4, IL-17, and IL-22) also tended to be suppressed. These results suggest that wearable OLED-based phototherapy can complement the limitations of existing treatments and offer a self-administered treatment strategy.

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Cite This Study

Shin et al. (2026) studied this question.

synapsesocial.com/papers/69a7cd3dd48f933b5eed9707https://doi.org/10.26599/nr.2026.94908607
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