Why the study?
The prevalence and morbidity of primary aldosteronism are increasingly acknowledged, yet it continues to be underdiagnosed due to limited screening and diagnostic complexity.
Population
133 relevant studies on primary aldosteronism
Design
Narrative review
Key result
Primary aldosteronism affects 5-10% of hypertensive patients and causes 13.6% major cardiovascular events at 5.8 years, with high underdiagnosis due to screening challenges.
Authors
Loading...
Warrants routine screening in resistant and young-onset hypertension; reinforces significant cardiovascular morbidity of underdiagnosed primary aldosteronism.
Primary aldosteronism is a common and underdiagnosed cause of secondary hypertension with significant cardiovascular and metabolic morbidity, requiring improved screening and diagnostic protocols.
Savvidis et al. (2026) studied this question. Primary aldosteronism affects 5-10% of hypertensive patients and causes 13.6% major cardiovascular events at 5.8 years, with high underdiagnosis due to screening challenges.