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March 4, 2026Cancer Epidemiology Biomarkers & Prevention0 citations

Head and Neck Cancers and Health Equity in the United States

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EDEdward Christopher DeeMWMichael P. WuNLNancy Y. Lee

Key Points

  • This research aims to investigate disparities in cancer outcomes, particularly in head and neck cancers, among different racial and socioeconomic groups.
  • Performed a population-based analysis of head and neck cancer patients
  • Examined the impact of neighborhood social vulnerability on diagnosis stages
  • Analyzed racial differences in cancer outcomes and access to care
  • Non-Hispanic Black and Hispanic patients showed higher odds of late-stage diagnosis
  • Social vulnerability amplified health outcome disparities
  • Addressing upstream factors can reduce racial differences in cancer outcomes

Abstract

Persistent inequities in cancer care in the United States shape outcomes across the entire cancer continuum, and head and neck cancers offer a compelling lens through which to examine these structural drivers. In their population-based analysis, Tortolero and colleagues demonstrate that non-Hispanic Black and Hispanic patients with oral cavity cancer experience markedly higher odds of late-stage diagnosis, with neighborhood-level social vulnerability further magnifying these disparities. These findings reinforce that delayed diagnosis reflects not individual behaviors but broader determinants, including socioeconomic precarity, transportation barriers, limited health literacy, and fragmented access to timely evaluation. Evidence across head and neck and other cancers, such as laryngeal and prostate malignancies, underscores that racial differences in outcomes often attenuate when upstream factors and access to high-quality care are addressed. Emerging qualitative and health services research highlights additional barriers and potential structural interventions. Advancing equity in head and neck oncology will require pairing tumor-specific advances with policies that expand access, coordination, and continuity of care. See related article by Tortolero et al., p. 398.

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Cite This Study

Dee et al. (2026) studied this question.

synapsesocial.com/papers/69a7cdaed48f933b5eeda37chttps://doi.org/10.1158/1055-9965.epi-25-1951
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neighborhood-Level Disadvantage and Delayed Adjuvant Therapy in Head and Neck Cancer2024 · 25 citations
  2. 2Association of Delayed Time to Treatment Initiation With Overall Survival and Recurrence Among Patients With Head and Neck Squamous Cell Carcinoma in an Underserved Urban Population2019 · 125 citations
  3. 3Patient Navigation for Timely, Guideline-Adherent Adjuvant Therapy for Head and Neck Cancer: A National Landscape Analysis2023 · 19 citations
  4. 4Association of Black Race With Prostate Cancer–Specific and Other-Cause Mortality2019 · 416 citations
  5. 5Definitive radiotherapy for nasopharyngeal carcinoma in Japan: analysis of cases in the National Head and Neck Cancer Registry from 2011 to 20142023 · 6 citations