Primary pancreatic lymphoma (PPL), which is defined as lymphoma originating from pancreatic lymphoid tissue or infiltrating lymphocytes, is a rare clinical manifestation with non - specific symptoms. Surgical resection is not regarded as the first - line treatment for PPL; however, it may be indicated for the management of complications or the clarification of diagnosis in challenging cases. Emergent laparocospic distal pancreatectomy with splenectomy (E-LDPS) has not been reported to treat emergent conditions of PPL. Herein, a 63 - year - old male who underwent emergency laparotomy due to acute intra - abdominal hemorrhage is presented. Intraoperative findings led to a radical LDPS due to suspected splenic rupture. Subsequently, histopathological examination confirmed primary diffuse large B - cell lymphoma of the pancreas. The patient completed a full - course chemotherapy regimen and achieved complete remission, with no recurrence observed during the follow - up period. This case highlights the potential significance of early minimally invasive surgical intervention in the management of PPL when emergent complications occur in high volume center.
Huang et al. (2026) studied this question.