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March 5, 2026Frontiers in Medicine2 citationsOpen Access

Validation of the Caprini risk assessment model and efficacy of perioperative nutritional support + preventive nursing in reducing DVT among high-risk older adults undergoing hip fracture surgery: a two-phase study

PLPingfang LiuTSTing ShuMLManhua Liu

Key Points

  • This study aims to validate the Caprini risk assessment model for predicting DVT and assess the impact of nutritional support and nursing on older adults with hip fractures.
  • Retrospective analysis of 112 older adults with hip fractures categorized into DVT and non-DVT groups for Phase 1.
  • Prospective randomization of all patients into control and intervention groups in Phase 2.
  • Utilization of ROC curves to determine the predictive accuracy of the Caprini scale.
  • Intervention group received preventive nursing and perioperative nutritional support; control group received routine care.
  • Comparison of nutritional status, DVT incidence, functional outcomes, and nursing satisfaction.
  • Higher Caprini scores were found in the DVT group compared to the non-DVT group (p < 0.05).
  • A significantly higher proportion (94.74%) of patients in the DVT group were classified as highest risk (≥5) compared to 70.27% in the non-DVT group (p < 0.05).
  • The AUC for predictive accuracy was 0.724 (95% CI: 0.657–0.791; p < 0.001).
  • The intervention group showed improved nutritional biomarkers, shorter hospital stays, better hip function, and lower DVT incidence (p < 0.05).
  • Nursing satisfaction was higher in the intervention group (p < 0.05).

Abstract

Objective To evaluate the predictive accuracy of the original Caprini risk assessment model for postoperative deep venous thrombosis (DVT) in older adult patients with hip fractures and to assess the effect of perioperative nutritional support combined with preventive nursing on nutritional status and DVT incidence. Methods A total of 112 older adult patients with hip fractures who underwent surgical treatment were included. Patients were retrospectively categorized as DVT ( n = 38) or non-DVT ( n = 74) groups for Phase 1 analysis. For Phase 2, all patients were prospectively randomized into a control or intervention group ( n = 56 each). The predictive accuracy of the original Caprini scale was analyzed using receiver operating characteristic (ROC) curves. The intervention group received preventive nursing (based on original Caprini scores) and perioperative nutritional support, while the control group received routine care. Nutritional status, functional outcomes, DVT incidence, and satisfaction were compared. Results The original Caprini score was higher in the DVT group ( p 0.05). Using the original classification (low: 0–1, moderate: 2, high: 3–4, highest: ≥5), the proportion of patients in the “highest risk” category (≥5) was significantly higher in the DVT group (94.74%) than in the non-DVT group (70.27%) ( p 0.05). The AUC was 0.724 (95% CI: 0.657–0.791; p 0.001). Postoperatively, the intervention group showed superior nutritional biomarkers (ALB, PA, Hb), shorter time to mobilization and hospital stay, better hip function (Harris score) and quality of life (SF-36), a lower DVT incidence ( p 0.05), and higher nursing satisfaction ( p 0.05). Conclusion The Caprini risk assessment model demonstrates predictive value for DVT risk in this population. The combined intervention of perioperative nutritional support and preventive nursing improves nutritional status, functional recovery, and reduces DVT incidence.

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69a91cbed6127c7a504bfa5bhttps://doi.org/10.3389/fmed.2026.1680122
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