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Synapse
March 5, 20260 citations

Molecular Characteristics, Potential Mechanisms, and Prognostic Gene Model of Younger Female Patients With Gastric Cancer.

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XLXiaoyi LuanLZLulu ZhaoWWWanqing Wang

Key Points

  • The research aims to explore the molecular characteristics and prognosis of younger female patients with gastric cancer.
  • Analyzed molecular profiles of younger female gastric cancer patients
  • Compared hormone-related pathways between younger and older female patients
  • Assessed overall survival differences between high-risk and low-risk groups
  • Younger female patients exhibited significant differences in hormone-related pathways compared to older patients
  • High-risk younger patients showed worse overall survival than low-risk counterparts
  • Younger females had a higher likelihood of being classified as high-risk than older females

Abstract

In conclusion, we provided the comprehensive molecular profiles of younger female GC patients and found that there was a significant difference in enriched hormone-related pathways between the younger group and the older group. Compared with older female patients, younger female patients were more likely to be in the high-risk group, which showed worse OS than low-risk patients.

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Cite This Study

Luan et al. (2026) studied this question.

synapsesocial.com/papers/69a91dedd6127c7a504c13e2https://doi.org/10.1002/cnr2.70469
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