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Synapse
March 5, 2026Intensive Care Medicine2 citationsOpen Access

Influence of multiple trauma on the effect of transfusion strategies in patients with traumatic brain injury: a sub-study of the HEMOTION trial

MBMarwan BourasFLFrançois LauzierDFDean A. Fergusson

Key Points

  • This investigation aims to evaluate how multiple trauma affects the efficacy of different transfusion strategies in traumatic brain injury cases.
  • Conducted as a sub-study of the HEMOTION trial
  • Compared liberal and restrictive transfusion strategies
  • Analyzed outcomes using the Glasgow Outcome Scale-Extended (GOS-E)
  • Multiple trauma status did not influence the effect of transfusion strategies on GOS-E scores
  • Further investigation is needed for patients undergoing emergency extracranial surgery

Abstract

Multiple trauma status was not associated with the effect of liberal vs. restrictive transfusion strategies on the GOS-E. Patients requiring emergency extracranial surgery may warrant further investigation.

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Cite This Study

Bouras et al. (2026) studied this question.

synapsesocial.com/papers/69a91f0ad6127c7a504c281ehttps://doi.org/10.1007/s00134-025-08290-5
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