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March 6, 20260 citationsOpen Access

Relationship Between Serum Levels of Unsaturated Fatty Acids and Type 2 Diabetes Mellitus: A Cross-Sectional Analysis of NHANES 2003-2004 and 2011-2012.

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SLShan LiuYLYing LiuGWGaoyi Wu

Key Points

  • The aim is to examine the relationship between serum unsaturated fatty acids and the prevalence of type 2 diabetes mellitus (T2DM).
  • Cross-sectional analysis using data from NHANES 2003-2004 and 2011-2012.
  • Assessment of serum levels of n-3, n-6, and n-9 fatty acids.
  • Comparison of fatty acid profiles in relation to T2DM prevalence.
  • Inversely associated n-3 and n-6 polyunsaturated fatty acids (PUFAs) with T2DM prevalence.
  • Positively associated n-9 monounsaturated fatty acids (MUFAs) with T2DM prevalence.
  • Variability in associations across different fatty acid types.

Abstract

Our findings suggest that several serum n-3 and n-6 PUFAs are inversely associated with T2DM prevalence, whereas some n-9 MUFAs are positively associated with T2DM prevalence. These findings provide comprehensive descriptive data on the serum fatty acid profile in relation to T2DM and underscore the heterogeneity of associations across individual fatty acid species.

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69aa6ee2531e4c4a9ff59145https://doi.org/10.1155/jdr/1153035
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