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Synapse
March 6, 20260 citations

Effect of Probiotic Supplementation on Reproductive Outcomes of Women With Polycystic Ovary Syndrome Who Are Candidates for Intrauterine Insemination: A Randomized, Double-Blind, Placebo-Controlled Trial.

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TBTahereh BehroozilakMFMahsa FarshadfarSJSamira Jahangard

Key Points

  • This research investigates the effect of probiotic supplementation on reproductive outcomes in women with PCOS.
  • Conducted a randomized, double-blind, placebo-controlled trial
  • Administered probiotics for 8 weeks
  • Targeted women with polycystic ovary syndrome who were candidates for intrauterine insemination
  • Probiotic supplementation increased endometrial thickness
  • Suggests a potential improvement in endometrial receptivity
  • Findings highlight the role of probiotics in reproductive health for women with PCOS

Abstract

Probiotic supplementation for 8 weeks in women with PCOS who were candidates for IUI was associated with higher endometrial thickness, indicating a potential role in improving endometrial receptivity.

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Cite This Study

Behroozilak et al. (2026) studied this question.

synapsesocial.com/papers/69aa7087531e4c4a9ff5a604https://doi.org/10.1002/edm2.70185
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Gut microbiota, a new approach to management of polycystic ovary syndrome: a systematic review, meta-analysis and meta-evidence of 26 randomized controlled trials2026 · 4 citations
  2. 2Efficacy of probiotic and synbiotic supplementation on metabolic and endocrine parameters in polycystic ovary syndrome: a meta-analysis of randomized controlled trials2026
  3. 3Effect of Pretreatment with Oral Contraceptive Pills on Intracytoplasmic Sperm Injection Outcome in Females with Polycystic Ovary Syndrome2025
  4. 4Effects of synbiotic supplementation on metabolic parameters and apelin in women with polycystic ovary syndrome: a randomised double-blind placebo-controlled trial2018 · 49 citations
  5. 5Effectiveness of Inositol Supplementation in Improving Ovulation Rates in PCOS2025