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March 8, 2026RSC Advances1 citationsOpen Access

A chitosan-based thermosensitive hydrogel incorporating propranolol nanoparticles to promote early osseointegration and peri-implant soft-tissue healing

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ZSZhongxi SunZZhiqiangSSShuang Song

Key Points

  • The aim is to assess the impact of a chitosan-based hydrogel with propranolol on osseointegration and tissue healing.
  • Developed a chitosan-based thermosensitive hydrogel
  • Incorporated propranolol nanoparticles into the hydrogel
  • Assessed the hydrogel's effects on peri-implant soft-tissue and osseointegration
  • The propranolol-loaded hydrogel enhanced osseointegration rates
  • Promoted improved healing of the gingival tissue around implants

Abstract

A propranolol-loaded thermosensitive chitosan hydrogel was developed to locally promote peri-implant osseointegration and gingival tissue healing.

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Cite This Study

Sun et al. (2026) studied this question.

synapsesocial.com/papers/69acc57d32b0ef16a404fbf4https://doi.org/10.1039/d6ra00103c
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