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March 8, 2026The Aging Male1 citationsOpen Access

Current treatment for erectile dysfunction: an umbrella review of systematic reviews and meta-analyses

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JMJian MaSecond Affiliated Hospital of Chengdu University of Traditional ChineseJWJintao WeiKey Laboratory of Guangdong ProvinceJLJinze LiSouth China Agricultural University

Key Points

  • The central aim is to assess the quality and effectiveness of treatments for erectile dysfunction (ED) based on existing systematic reviews and meta-analyses.
  • Conducted an umbrella review of systematic reviews and meta-analyses on ED treatments.
  • Included both pharmacological and nonpharmacological interventions.
  • Evaluated the quality of evidence and outcomes reported.
  • Statistically significant improvements in ED were noted for both treatment types.
  • Overall quality of evidence was found to be low or very low.
  • Recommendations for further high-quality studies and meta-analyses were highlighted.

Abstract

The current evidence base for ED treatments is predominantly of low or very low quality. While statistically significant improvements in ED were observed with both pharmacological and nonpharmacological interventions, these findings should be interpreted with caution due to the limited number of patients and the subjective nature of outcome indicators. The treatment landscape for ED is increasingly diverse, yet the reliability of the evidence is poor. Further well-designed studies on single treatments and high-quality meta-analyses of intertreatment comparisons are urgently recommended.

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Cite This Study

Ma et al. (2026) studied this question.

synapsesocial.com/papers/69ada8cfbc08abd80d5bc19bhttps://doi.org/10.1080/13685538.2026.2640765
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