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March 10, 2026Virology Journal0 citationsOpen Access

Varicella zoster virus–related myelitis: a case series and literature review

ZSZhijiao SongRLRuohao LiLLLantao Liang

Key Points

  • The study aims to explore the clinical features and treatment outcomes of varicella zoster virus-related myelitis.
  • Conducted a case series analysis of patients with myelitis associated with varicella zoster virus.
  • Utilized magnetic resonance imaging for early diagnosis.
  • Performed CSF molecular testing to confirm infection.
  • Administered antiviral and immunomodulatory therapies.
  • Myelitis may present without a rash, complicating diagnosis.
  • Early imaging and testing are critical for timely treatment.
  • Combination therapies showed potential improvement in neurological outcomes.

Abstract

VZVM presents with diverse clinical manifestations and may occur without the typical vesicular rash. It can develop either during the initial phase of VZV infection or as a delayed complication. Early magnetic resonance imaging and CSF molecular testing support timely diagnosis. Prompt and adequate antiviral therapy combined with immunomodulatory treatment may improve neurological outcomes.

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Cite This Study

Song et al. (2026) studied this question.

synapsesocial.com/papers/69af95b470916d39fea4d95bhttps://doi.org/10.1186/s12985-026-03123-3
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