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Synapse
March 10, 20260 citations

Infiltrated Facial Plaques With 40-Year Evolution.

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AAAndreia Akina AkamineMMMaiara Christine MacagnanHMHelena Zenedin Marchioro

Key Points

  • This research aims to examine the characteristics and diagnostic challenges of chronic infiltrative facial plaques.
  • Histopathological examination of the plaque
  • Identification of granulomatous process
  • Review of microbiological special stains
  • Granulomatous process confirmed through histopathology
  • Negative microbiological special stains
  • Long-term monitoring emphasized for accurate diagnosis of chronic conditions

Abstract

An elderly woman presented with a chronic, infiltrative plaque on the nasal dorsum and malar region, persisting for decades. Histopathology revealed a granulomatous process, but the etiology remained uncertain despite extensive investigation. This case illustrates the diagnostic challenge of a slowly progressive facial plaque with tuberculoid granulomas and negative microbiological special stains, highlighting the importance of clinicopathological correlation and follow-up in endemic areas for chronic granulomatous dermatoses.

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Cite This Study

Akamine et al. (2026) studied this question.

synapsesocial.com/papers/69af95c070916d39fea4d9e7https://doi.org/10.1111/ijd.70377
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