The study aims to evaluate the therapeutic effects of mesenchymal stromal cells on intestinal health in a preterm piglet model of necrotizing enterocolitis.
Utilized a preterm piglet model of necrotizing enterocolitis.
Administered mesenchymal stromal cell therapy to assess its effects.
Monitored changes in intestinal integrity and inflammation levels.
Demonstrated improved intestinal integrity in treated piglets.
Reduced inflammation observed in the intestinal tissues.
Support for the potential application of MSC therapy in clinical settings.
Abstract
This is the first study to demonstrate therapeutic benefit of MSCs in a preterm piglet NEC model, supporting their potential use in translational NEC therapies.