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March 12, 2026Open Access Emergency MedicineOpen Access

Predictive Value of Systemic Immune-Inflammation Index Combined with D-Dimer Levels and Injury Severity Score for the Prognosis of Patients with Multiple Injuries: A Retrospective Analysis

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Authors

XDXinlong DuYHYongming HeXLXia Liu

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Overview

Retrospective analysis predicts outcomes in multiple injuries using immune-inflammation index, D-dimer, and injury severity score, indicating clinical relevance.

Key Points

  • The study aims to evaluate the prognostic value of combining systemic immune-inflammation index, D-dimer, and injury severity score in patients with multiple injuries.
  • Analyzed 142 patients with multiple injuries retrospectively from an emergency department.
  • Categorized patients into survival and non-survival groups based on postoperative outcomes.
  • Used logistic regression for significant indicators to determine prognostic factors.
  • Assessed predictive value via receiver operating characteristic curves.
  • Median SII significantly differed between survival (340.11) and non-survival (849.93) groups (P<0.001).
  • SII, D-D, and ISS were identified as independent prognostic factors for mortality.
  • Combination of SII, D-D, and ISS showed high predictive accuracy (AUC=0.969) for 28-day mortality.
  • Patients with SII ≤ 308.8 had significantly lower mortality (P<0.05).

Cite This Study

Du et al. (2026) studied this question.

synapsesocial.com/papers/69b2581996eeacc4fcec7642https://doi.org/10.2147/oaem.s549167
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