laparoscopy (n = 1), retroperitoneoscopic resection (n = 1), and hybrid laparoscopicinguinotomic approach for a trans-compartment lesion (n=1).We collected clinical, surgical, and oncologic data.A topographic surgical approach based on retroperitoneal vascular areas was used.Results: Mean tumor size was 65 mm.Histological subtypes included well differentiated liposarcoma (n = 1), a small paravescical local recurrence of dedifferentiated liposarcoma (n=1), leiomyosarcoma (n = 5), solitary fibrous tumor (n = 3), and a perisplenic local recurrence of solitary fibrous tumor (N=1).No conversions to open surgery nor intraoperative complications were observed.Complete resection was achieved in all patients.Median operative time was 260 minutes, with an average hospital stay of 6 days.Only one patient experienced a significant postoperative complication (i.e.subcutaneous abscess, treated with surgical drainage).Conclusions: Minimally invasive resection of sarcomas is safe and feasible in selected patients when performed in expert centers.Several minimally invasive techniques and different trocars setups are available depending on tumor location, allowing to gather the best possible access to retroperitoneal structures.Good sarcoma center clinical practice principles should still be followed, with preoperative biopsy and a histology-oriented surgery.To our knowledge, this is the first systematic case series on the subject, and it lays the basis for a reproducible surgical setup.Matched multicenter studies are needed to further define patient selection criteria and establish long-term outcomes non-inferiority.
Saidi et al. (2026) studied this question.