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March 13, 20260 citations

Flowable Extracellular Matrix Hydrogel to Prevent Adhesion Formation Following Flexor Tendon Repair: A Preclinical Study.

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PSP Alex SmithTKTimothy J. KeaneFMFrida K. Montoya

Key Points

  • This research aims to evaluate the efficacy of flowable ECM hydrogel in preventing adhesions after flexor tendon repair.
  • Utilized flowable ECM hydrogel and ECM mesh in a preclinical model for tendon repair.
  • Assessed adhesion formation and tendon mechanics post-application.
  • Compared outcomes between hydrogel and mesh interventions.
  • Flowable ECM hydrogel significantly reduced adhesion formation compared to control.
  • Preserved tendon mechanics were observed following the use of the hydrogel, highlighting its effectiveness.
  • Hydrogel application was noted for its ease and practicality in surgical settings.

Abstract

Flowable ECM hydrogel and ECM mesh significantly reduce adhesions and preserve tendon mechanics after flexor tendon repair. The hydrogel's flowable form offers superior ease of application, addressing unmet clinical needs.

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Cite This Study

Smith et al. (2026) studied this question.

synapsesocial.com/papers/69b3ab2902a1e69014ccbc62https://doi.org/10.1097/prs.0000000000013021
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