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March 14, 2026Lab on a Chip0 citationsOpen Access

Multiphasic droplet microfluidics platform for controlled bacteria and mammalian cell coculture

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IAIbraheem AlshareedahAKAnand Kumar

Key Points

  • To address the challenges in coculturing mammalian cells and bacteria using a microfluidics approach.
  • Utilized a multiphasic droplet microfluidics platform to enable controlled coculture.
  • Investigated compatibility between mammalian cells and bacteria in a miniaturized environment.
  • Optimized growth conditions for both cell types in microfluidic systems.
  • Demonstrated enhanced spatial control in coculture conditions.
  • Achieved high-throughput biological assays using the droplet platform.
  • Revealed improved growth for both bacteria and mammalian cells in the designed microfluidic system.

Abstract

Microfluidics has revolutionized high-throughput miniaturized biological assays. However, coculture of mammalian cells and bacteria remains challenging in microfluidic systems due to incompatible growth requirements, limited spatial control, and the requirement...

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Cite This Study

Alshareedah et al. (2026) studied this question.

synapsesocial.com/papers/69b4b9fb18185d8a398023c3https://doi.org/10.1039/d6lc00016a
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