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March 14, 2026Clinics0 citationsOpen Access

Incidence of intra-abdominal hypertension after liver transplantation with temporary portocaval shunt – A prospective cohort

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EMEstrella Bianca MeloLCLuiz Augusto Carneiro-D’AlbuquerqueWAWellington Andraus

Key Points

  • The study aimed to evaluate the incidence of intra-abdominal hypertension after liver transplantation and its associated complications.
  • Studied 104 patients undergoing liver transplantation with temporary portocaval shunt.
  • Measured intra-abdominal pressure and abdominal perfusion pressure post-surgery.
  • Divided patients into two groups based on presence of intra-abdominal hypertension.
  • Analyzed outcomes including mechanical ventilation, hemodialysis, and graft function.
  • Intra-abdominal hypertension occurred in 14.4% of patients.
  • 60% of the IAH+ group required mechanical ventilation compared to 26.7% in the IAH- group (p = 0.016).
  • The need for hemodialysis was significantly higher in the IAH+ group (31.3% vs. 10.8%, p = 0.047).
  • No cases of abdominal compartment syndrome were noted.
  • Similar reoperation, retransplant, and death rates were observed between groups.

Abstract

• The incidence of intrabdominal hypertension was low in this study. • IAH was linked to a greater need for mechanical ventilation. • IAH was linked to a greater need for hemodialysis. • No cases of abdominal compartment syndrome were observed. Intra-Abdominal Hypertension (IAH) is reported to be frequent after liver transplantation. Nonetheless, the evolution of surgical techniques improved postoperative care in the last decades, which could lead to a lower incidence of Intra-abdominal hypertension. The authors prospectively studied 104 patients. The intra-abdominal pressure and abdominal perfusion pressure were measured at the end of surgery and every 6 hours until 72 hours, and patients were divided into two groups: with (IAH + ) or without (IAH - ) IAH. Outcomes analyzed were death, renal function, reoperation, need for vasopressors, mechanical ventilation, hemodialysis, and graft function measured by indocyanine green. The incidence of Intra-abdominal hypertension was 14.4%, with no abdominal compartment syndrome cases. After 48 hours, 60% of the IAH + group was on mechanical ventilation versus 26.7% in the IAH - group ( p = 0.016). The prevalence of dialysis at the end of the first postoperative week was higher in the IAH + group (31.3% vs. 10.8%, p = 0.047). Both groups had similar indocyanine green clearance on the third and seventh postoperative days. Reoperation rates (12.4% vs. 20%), need for retransplant (10.1% vs. 13.3%), and death (14% vs. 18.2%) were similar in IAH - and IAH + groups, respectively. The number of blood products transfused (OR = 1.18) and body mass index (OR = 1.10) were associated with the development of intra-abdominal hypertension, while intraoperative ascites (OR = 0.19) was a protective factor. Intra-abdominal hypertension was present in 14.4% of liver transplant patients, and IAH was linked to a greater need for mechanical ventilation and hemodialysis but not to more reoperations, transplants, or deaths.

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Cite This Study

Melo et al. (2026) studied this question.

synapsesocial.com/papers/69b4fb1bb39f7826a300badfhttps://doi.org/10.1016/j.clinsp.2026.100900
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