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March 14, 2026Journal of Materials Chemistry B0 citations

Porous organic polymers based on deep-cavity calixarene for broad-spectrum and high-affinity drug adsorption in gastrointestinal tract

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WCWei-Yan ChenXCXiao-Min CaoAYAn-Kang Ying

Key Points

  • The aim is to explore the use of porous organic polymers based on deep-cavity calixarene for enhancing drug adsorption in the gastrointestinal tract.
  • Synthesis of porous organic polymers using calixarene.
  • Evaluation of drug adsorption capacity through laboratory experiments.
  • Analysis of adsorption efficiency under various gastrointestinal conditions.
  • Demonstrated high-affinity drug adsorption with the calixarene-based polymers.
  • Showed effective mitigation of local side effects from drugs in the digestive tract.
  • Indicated potential for immediate intervention in drug overdose situations.

Abstract

Gastrointestinal adsorption of drugs holds significant clinical value for mitigating local side effects in the digestive tract and enabling immediate intervention in cases of drug overdose. However, the complex gastrointestinal...

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69b4fc0eb39f7826a300cb08https://doi.org/10.1039/d5tb02700d
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