Zeolite hemostatic dressings have attracted much attention due to promoting blood coagulation through physical absorption and ion exchange. However, during the absorption process, zeolites release a substantial amount of heat, which might induce thermal injury and potentially lead to tissue necrosis. Thus, it is significant to construct an effective zeolite‐based hemostatic material with safe hemostasis. Herein, we designed a novel hemostatic phase change bandage via electrospinning, composed of 5A zeolites and phase change materials, for efficient hemostasis and temperature control. This strategy relies on the inherent properties of phase change materials to absorb heat at constant temperature to achieve thermal protection. The solid–solid phase change membrane involved in the hemostatic bandage, synthesized from polyethylene glycol and 4,4′‐methylene‐bis(cyclohexyl isocyanate), overcomes the shortcomings of leakage and rigidity of traditional phase change materials and exhibits a proper phase transition temperature by adjusting the cross‐linking density. Additionally, the flexible hemostatic phase change bandage shows thermal stability, strong mechanical strength, and excellent infiltration. Moreover, the hemostatic phase change bandage effectively maintained a temperature below 42.6 °C during hemostasis, surpassing that of pure 5A by 58.3 °C and a commercial product by 3.6 °C. This work provides a new strategy for eliminating thermal injury in wound hemostasis and broadens the application of phase change materials in the medical field.
Zhang et al. (2026) studied this question.