Efficacy and Safety of Pulsed Low-Dose Rate Radiotherapy in Re-Irradiation of Recurrent Solid Tumors

Key Points

• This research examines the efficacy and safety of pulsed low-dose rate radiotherapy in recurrent solid tumors.
• Evaluated pulsed low-dose rate radiotherapy (PLDR) for re-irradiation of recurrent solid tumors.
• Analyzed patient characteristics such as IDH1 mutation status, recurrence location, and re-irradiation interval.
• PLDR re-irradiation shows favorable efficacy and safety in recurrent solid tumors.
• Patients with IDH1 mutation and nontemporal lobe recurrence benefit more from PLDR.
• Longer re-irradiation intervals (>24 months) are associated with greater treatment advantages.