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March 15, 2026Revista chilena de enfermedades respiratorias0 citationsOpen Access

Tuberculosis congénita una patología rara pero presente: reporte de caso

MBMónica Holguín B.LALorena García A.SBSharon Medina B.

Key Points

  • To highlight the significance of recognizing congenital tuberculosis as a critical health issue in newborns.
  • Presented a case of a premature newborn diagnosed with congenital tuberculosis.
  • Monitored the infant's response to tetravalent treatment.
  • Documented complications and outcomes related to maternal health.
  • Newborn diagnosed with sensitive congenital pulmonary tuberculosis.
  • Favorable response to treatment with a negative culture at two months.
  • Neonatal mortality occurred due to neurological complications after three months.

Abstract

Congenital tuberculosis a rare but present pathology: case reportCongenital tuberculosis is identified as one of the main causes of infectious mortality in childhood, particularly in children under five years old.In newborns, tuberculosis is rarely included within the diagnostic spectrum of causes of sepsis; late identification can contribute to a high mortality rate for the mother-child pair.The case of a premature male newborn at 30 weeks in the context of maternal mortality is presented, who was diagnosed with severe perinatal asphyxia and sensitive congenital pulmonary tuberculosis, with a favorable response to tetravalent treatment, with a negative culture control at two months; however, he died in the third month of treatment due to neurological complications.Additionally, it was not possible to establish the diagnosis of maternal tuberculosis, because she was admitted to the emergency room at 30 weeks of gestation, without prenatal care due to obstructive shock.This case highlights the importance of prenatal care and the identification of curable pathologies such as tuberculosis at this stage.

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Cite This Study

B. et al. (2025) studied this question.

synapsesocial.com/papers/69b64ccdb42794e3e660dedbhttps://doi.org/10.4067/s0717-73482025000400278
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Congenital Tuberculosis in a 2-Week-Old Neonate With an Asymptomatic Mother2026
  2. 2Disseminated Tuberculosis With Cavitary Lung Disease in a Very Preterm Infant2026
  3. 3Comparative analysis of clinical manifestations between congenital and non-congenital tuberculosis in infants2026
  4. 4A70-48 When Prevention Fails: Pulmonary Tuberculous Abscess in a Malnourished Unvaccinated Infant2026
  5. 5Placental Tuberculosis: A Microscopic Portrait of a Rare Diagnosis2026