PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
March 17, 2026The Brazilian Journal of Infectious DiseasesOpen Access

Molecular Characterization of Carbapenemase Co-Production in Klebsiella Pneumoniae

View Full Paper
Ask AI
Bookmark
Share

Authors

PGPatrícia Guedes GarciaAAAna Clara de Lelis AraújoANAlessandra Figueiredo de Castro Nassar

Discussion

Loading...

Member takes

Overview

Cross-sectional study investigates carbapenemase genes in Klebsiella pneumoniae, highlighting serious clinical implications.

Key Points

  • The research aims to determine the prevalence and identify the genes encoding carbapenemases in carbenem-resistant K. pneumoniae strains.
  • Cross-sectional study design conducted at a public hospital in Brazil.
  • Carbapenem-resistant K. pneumoniae strains were collected from clinical samples.
  • Species identification was performed via phenotypic methods and confirmed by mass spectrometry.
  • Carbapenemase genes were detected using real-time polymerase chain reaction (qPCR).
  • 56.71% of isolates possessed the blaKPC gene; 10.44% had the blaNDM gene.
  • Co-production of blaKPC and blaNDM occurred in 31.35% of samples.
  • Only 1.5% showed co-production of blaKPC and blaOXA-48.
  • Co-production cases were exclusively found in 2023, making up 59.45% of analyzed strains that year.

Cite This Study

Garcia et al. (2026) studied this question.

synapsesocial.com/papers/69b8ef52deb47d591b8c556chttps://doi.org/10.1016/j.bjid.2026.104650
View Full Paper
Ask AI
Bookmark
Share