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March 18, 2026Annals of Pediatric Cardiology0 citationsOpen Access

Unusual presentation of left atrial myxoma in a child mimicking acute poststreptococcal glomerulonephritis

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MRMaulana RosyadyARAnisa RahmadhanyMPMuhammad Arza Putra

Key Result

Left atrial myxoma in children can present with nephritic-like features mimicking acute poststreptococcal glomerulonephritis due to low cardiac output and venous congestion.

Key Points

  • To highlight the misdiagnosis of cardiac myxoma as poststreptococcal glomerulonephritis in a child.
  • Case report of a 14-year-old boy.
  • Initial diagnosis included assessments like hematuria and anti-streptolysin-O titers.
  • Echocardiography was used for further evaluation of respiratory and cardiac symptoms.
  • Surgical excision confirmed the diagnosis.
  • Patient initially displayed symptoms of nephritic syndrome.
  • Echocardiography revealed a large left atrial mass and impaired heart function.
  • Surgical excision confirmed a myxoma, clarifying the diagnosis.
  • Symptoms were linked to low cardiac output rather than renal disease.

Structured PICO

P
Population
14-year-old boy initially diagnosed with acute poststreptococcal glomerulonephritis (hematuria, mild proteinuria, elevated anti-streptolysin-O titers) presenting with worsening dyspnea, edema, and signs of heart failure.
I
Intervention
Echocardiography and surgical excision of left atrial mass
O
Outcome
Diagnosis and surgical excision of left atrial myxoma

Cardiac myxomas in children can mimic acute poststreptococcal glomerulonephritis due to low cardiac output and venous congestion, highlighting the importance of considering cardiac causes in atypical presentations.

Abstract

Cardiac myxomas are rare in children and can mimic other conditions. We report a 14-year-old boy initially diagnosed with acute poststreptococcal glomerulonephritis based on hematuria, mild proteinuria, and elevated anti-streptolysin-O titers. However, worsening dyspnea, edema, and signs of heart failure prompted further evaluation. Echocardiography revealed a large left atrial mass with impaired biventricular function and tricuspid regurgitation. Surgical excision confirmed a myxoma. The patient’s renal and systemic symptoms were attributed to low cardiac output and venous congestion, not true glomerulonephritis. This case highlights the need to consider cardiac causes in pediatric patients with persistent nephritic-like features.

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Cite This Study

Rosyady et al. (2025) studied this question. Left atrial myxoma in children can present with nephritic-like features mimicking acute poststreptococcal glomerulonephritis due to low cardiac output and venous congestion.

synapsesocial.com/papers/69ba429c4e9516ffd37a304fhttps://doi.org/10.4103/apc.apc_159_25
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