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March 19, 2026Acta Medica Bulgarica2 citationsOpen Access

Cleft Lip and/or Palate: A Comprehensive Review and our Treatment Approach

KGKostadin GigovIGIvan GinevMMM. Miteva

Key Points

  • The aim is to provide a thorough understanding of cleft lip and palate, including challenges, treatment, and outcomes.
  • Reviewed epidemiology and developmental processes related to cleft conditions.
  • Examined environmental and genetic risk factors and their interactions.
  • Discussed current treatment recommendations and assessment practices.
  • Evaluated commonly used surgical techniques and associated clinical outcomes.
  • Identified key environmental and genetic factors influencing cleft conditions.
  • Highlighted significant improvements in clinical outcomes following surgical intervention.
  • Documented complications arising from surgical repair and emphasized need for ongoing research.

Abstract

Abstract Cleft lip with or without cleft palate is the most common congenital malformation of the head and neck. Children with cleft anomalies may experience a multitude of physical and developmental challenges. Psychosocial and emotional concerns of the patients and their families can also occur. As such, comprehensive care for the patient with cleft lip and/or palate requires an interdisciplinary team. This article describes epidemiology, embryo-logical developmental processes, known environmental and genetic risk factors, and their interaction, the assessment and current treatment recommendations for children born with cleft lip and/or cleft palate. We review the commonly used surgical techniques for repair, clinical outcomes and complications. Throughout the discussion, we share our experience and identify areas for future study with the focus on cleft palate management.

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Cite This Study

Gigov et al. (2026) studied this question.

synapsesocial.com/papers/69bb92ae496e729e6298024fhttps://doi.org/10.2478/amb-2026-0049
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fetal Cleft Lip and Palate2026
  2. 2Characteristics of Factors Influencing the Occurrence of Cleft Lip and/or Palate: A Case Analysis and Literature Review2024 · 11 citations
  3. 3Characteristics of Factors Influencing the Occurrence of Cleft Lip and/or Palate: A Case Analysis and Literature Review2024
  4. 4Genetic and Molecular Basis of Cleft Lip and Palate: A Comprehensive Review2026
  5. 5Multidisciplinary Treatment in a Patient with Cleft Lip and Palate: A Case Report2024 · 1 citations