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March 19, 20262 citations

Serologic response to VDRL in infants with congenital syphilis: ceftriaxone vs. penicillin.

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ACAna Nery Melo CavalcanteMAMaria Alix Leite AraújoBSBeatriz Sobreira Camilo Soares

Key Points

  • The study aims to compare the serological responses to VDRL in infants with congenital syphilis treated with ceftriaxone or penicillin.
  • Infants diagnosed with congenital syphilis were treated with either ceftriaxone or penicillin.
  • Serological responses were monitored using the VDRL test.
  • Complications related to congenital syphilis were recorded.
  • No significant difference in VDRL response between the two treatment groups.
  • Ceftriaxone-treated infants did not experience kernicterus or other complications related to congenital syphilis.

Abstract

Serological response to VDRL was comparable between infants treated with ceftriaxone and those treated with penicillin. No cases of kernicterus or other CS-related complications occurred among ceftriaxone-treated infants.

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Cite This Study

Cavalcante et al. (2026) studied this question.

synapsesocial.com/papers/69bb9321496e729e62980fa3https://doi.org/10.1016/j.jped.2026.101530
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