Mucosal tenofovir 1% gel stimulates cell proliferation and type I/III interferon pathways

Key Points

• The aim is to assess the effects of mucosal tenofovir 1% gel on cell proliferation and interferon pathways.
• Conducted multiple clinical trials registered with ClinicalTrials.gov.
• Administered tenofovir 1% gel to participants to evaluate mucosal responses.
• Analyzed cell proliferation and type I/III interferon pathways.
• Mucosal tenofovir gel significantly stimulates cell proliferation.
• Activation of type I and III interferon pathways was observed.