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July 24, 2013New England Journal of Medicine1,359 citationsOpen Access

Riociguat for the Treatment of Pulmonary Arterial Hypertension

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HGHossein Ardeschir GhofraniNGNazzareno GalièFGFriedrich Grimminger

Structured PICO

Does riociguat improve exercise capacity in patients with pulmonary arterial hypertension?

P
Population
Patients with pulmonary arterial hypertension
I
Intervention
Riociguat
O
Outcome
Exercise capacitysurrogate

Riociguat provides significant improvement in exercise capacity for patients with pulmonary arterial hypertension.

Abstract

Riociguat significantly improved exercise capacity and secondary efficacy end points in patients with pulmonary arterial hypertension. (Funded by Bayer HealthCare; PATENT-1 and PATENT-2 ClinicalTrials.gov numbers, NCT00810693 and NCT00863681, respectively.).

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Cite This Study

Ghofrani et al. (2013) studied this question.

synapsesocial.com/papers/69c42fdeb92fe965c90861dahttps://doi.org/10.1056/nejmoa1209655
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