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Synapse
March 26, 20260 citations

Risk factors for nonresolving neurological deficits after spinal meningioma surgery: an integrated clinical and volumetric analysis of 202 patients.

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OAObada T AlhalabiMMMustafa Ahmed MahmutogluAAAhmed Gamal Abouarab

Key Points

  • To identify risk factors associated with nonresolving neurological deficits following spinal meningioma surgery.
  • Analyzed a cohort of 202 patients with spinal meningioma
  • Conducted volumetric assessments
  • Evaluated preoperative neurological status and Ki-67 index
  • Older age correlated with higher risk of ongoing neurological deficits
  • Low Ki-67 index was associated with nonresolving symptoms
  • Early intervention in younger patients linked to better long-term neurological outcomes

Abstract

This volumetry-informed series of patients with SM revealed older age and a low Ki-67 index, along with preoperative neurological deficits, constitute a higher risk of nonresolving neurological symptoms after resection. An early surgical intervention in oligosymptomatic young patients could therefore help preserve excellent long-term neurological function.

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Cite This Study

Alhalabi et al. (2026) studied this question.

synapsesocial.com/papers/69c4cd25fdc3bde4489190f1https://doi.org/10.3171/2025.10.spine25813
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